Vitamin e
Berocca Pn, M.v.c. 9+, M.v.i, M.v.i. Lyophilized, Mvc, Vitaped (vitamin e) is an unknown pharmaceutical. Vitamin e was first approved as M.v.i.-12 lyophilized on 1985-08-08. It is used to treat alzheimer disease, drug-induced dyskinesia, hemolytic anemia, and vitamin e deficiency in the USA.
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Commercial
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Drug Products
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EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Ascorbic acid
+
Biotin
+
Cyanocobalamin
+
Dexpanthenol
+
Ergocalciferol
+
Folic acid
+
Niacinamide
+
Phytonadione
+
Pyridoxine hydrochloride
+
Riboflavin 5'-phosphate sodium
+
Thiamine hydrochloride
+
Vitamin a
+
Vitamin e
Ascorbic acid
+
Biotin
+
Cyanocobalamin
+
Dexpanthenol
+
Ergocalciferol
+
Folic acid
+
Niacinamide
+
Pyridoxine
+
Riboflavin 5'-phosphate sodium
+
Thiamine
+
Vitamin a
+
Vitamin e
Ascorbic acid
+
Biotin
+
Cyanocobalamin
+
Dexpanthenol
+
Ergocalciferol
+
Folic acid
+
Niacinamide
+
Pyridoxine hydrochloride
+
Riboflavin
+
Thiamine hydrochloride
+
Vitamin a
+
Vitamin e
Ascorbic acid
+
Biotin
+
Cyanocobalamin
+
Dexpanthenol
+
Ergocalciferol
+
Folic acid
+
Niacinamide
+
Pyridoxine hydrochloride
+
Riboflavin 5'-phosphate sodium
+
Thiamine hydrochloride
+
Vitamin a
+
Vitamin e
Ascorbic acid
+
Biotin
+
Cyanocobalamin
+
Dexpanthenol
+
Ergocalciferol
+
Folic acid
+
Niacinamide
+
Pyridoxine hydrochloride
+
Riboflavin 5'-phosphate sodium
+
Thiamine hydrochloride
+
Vitamin a
+
Vitamin e
+
Vitamin k
Ascorbic acid
+
Biotin
+
Cyanocobalamin
+
Dexpanthenol
+
Ergocalciferol
+
Folic acid
+
Niacinamide
+
Pyridoxine hydrochloride
+
Riboflavin 5'-phosphate sodium
+
Thiamine hydrochloride
+
Vitamin a palmitate
+
Vitamin e
Labels
FDA
EMA
Brand Name | Status | Last Update |
|---|---|---|
| 1.8oz armstrong hand sanitizer with aloe vera and vitamin e | OTC monograph not final | 2017-12-15 |
| 2 pack assured instant hand sanitizer with moisturizers (vitamin e and aloe) | OTC monograph not final | 2014-11-02 |
| 25 person ansi | OTC monograph final | 2010-06-07 |
| 3 hand sanitizers | OTC monograph not final | 2014-11-15 |
| 3 pack assured instant hand sanitizer with moisturizers (vitamin e and aloe) | OTC monograph not final | 2014-11-02 |
| 3 pack assured instant hand sanitizer with moisturizers (vitamin e and moisturizers) | OTC monograph not final | 2014-11-02 |
| 3 pack family dollar instant hand sanitizers | OTC monograph not final | 2014-11-28 |
| 50 person ansi | OTC monograph final | 2010-06-07 |
| 7-11 instant hand sanitizer with aloe and vitamin e | OTC monograph not final | 2011-11-02 |
| a and d | OTC monograph final | 2020-01-07 |
Show 417 more
Indications
FDA
EMA
Indication | Ontology | MeSH | ICD-10 |
|---|---|---|---|
| alzheimer disease | EFO_0000249 | D000544 | F03 |
| drug-induced dyskinesia | EFO_1000904 | D004409 | — |
| hemolytic anemia | — | D000743 | D55-D59 |
| vitamin e deficiency | — | D014811 | E56.0 |
Agency Specific
FDA
EMA
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Patent Expiration
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No data
Clinical
Clinical Trials
1377 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Neoplasms | D009369 | — | C80 | 12 | 7 | 4 | 4 | 8 | 31 |
| Osteoarthritis | D010003 | EFO_0002506 | M15-M19 | — | 1 | — | 8 | 17 | 26 |
| Non-alcoholic fatty liver disease | D065626 | EFO_0003095 | K75.81 | 1 | 8 | 4 | 5 | 9 | 25 |
| Obesity | D009765 | EFO_0001073 | E66.9 | 4 | 3 | 3 | 2 | 14 | 24 |
| Knee osteoarthritis | D020370 | EFO_0004616 | M17 | — | — | — | 8 | 14 | 22 |
| Colorectal neoplasms | D015179 | — | — | 8 | 6 | 3 | 1 | 4 | 20 |
| Oxidative stress | D018384 | EFO_1001905 | — | — | 3 | 1 | 1 | 12 | 17 |
| Type 2 diabetes mellitus | D003924 | EFO_0001360 | E11 | 6 | 4 | 1 | 1 | 5 | 16 |
| Covid-19 | D000086382 | — | U07.1 | — | 5 | 3 | 1 | 8 | 15 |
| Male infertility | D007248 | EFO_0004248 | N46 | 1 | 2 | — | 2 | 8 | 13 |
Show 89 more
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Healthy volunteers/patients | — | — | — | 62 | 4 | 2 | — | 18 | 85 |
| Cardiovascular diseases | D002318 | HP_0001626 | — | — | 5 | 7 | — | 13 | 23 |
| Breast neoplasms | D001943 | EFO_0003869 | C50 | 6 | 8 | 1 | — | 5 | 20 |
| Anemia | D000740 | HP_0001903 | D64.9 | 2 | 4 | 5 | — | 10 | 20 |
| Inflammation | D007249 | MP_0001845 | — | 1 | 2 | 1 | — | 14 | 17 |
| Chronic obstructive pulmonary disease | D029424 | EFO_0000341 | J44.9 | 4 | 5 | 1 | — | 7 | 17 |
| Hiv infections | D015658 | EFO_0000764 | B20 | 3 | 2 | 8 | — | 2 | 15 |
| Prostatic neoplasms | D011471 | — | C61 | 4 | 4 | 4 | — | 2 | 14 |
| Alzheimer disease | D000544 | EFO_0000249 | F03 | 5 | 2 | 4 | — | 1 | 12 |
| Chronic kidney failure | D007676 | EFO_0003884 | N18.6 | — | 4 | 3 | — | 5 | 11 |
Show 123 more
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Asthma | D001249 | EFO_0000270 | J45 | 4 | 5 | — | — | 3 | 12 |
| Non-small-cell lung carcinoma | D002289 | — | — | 7 | 4 | — | — | — | 10 |
| Pancreatic neoplasms | D010190 | EFO_0003860 | C25 | 6 | 1 | — | — | 1 | 8 |
| Cystic fibrosis | D003550 | EFO_0000390 | E84 | — | 3 | — | — | 4 | 7 |
| Ovarian neoplasms | D010051 | EFO_0003893 | C56 | 4 | 3 | — | — | — | 6 |
| Melanoma | D008545 | — | — | 5 | 2 | — | — | — | 5 |
| Myelodysplastic syndromes | D009190 | — | D46 | 3 | 2 | — | — | — | 4 |
| Glioblastoma | D005909 | EFO_0000515 | — | 2 | 3 | — | — | — | 4 |
| Multiple sclerosis | D009103 | EFO_0003885 | G35 | 2 | 2 | — | — | 1 | 4 |
| B-cell chronic lymphocytic leukemia | D015451 | — | C91.1 | 3 | 1 | — | — | — | 3 |
Show 88 more
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Rheumatoid arthritis | D001172 | EFO_0000685 | M06.9 | 2 | — | — | — | 12 | 14 |
| Stroke | D020521 | EFO_0000712 | I63.9 | 2 | — | — | — | 9 | 11 |
| Iron deficiencies | D000090463 | — | E61.1 | 1 | — | — | — | 4 | 5 |
| Bacterial infections | D001424 | — | A49 | 2 | — | — | — | 2 | 4 |
| Hypersensitivity | D006967 | HP_0012393 | T78.40 | 1 | — | — | — | 3 | 4 |
| Macular edema | D008269 | — | — | 3 | — | — | — | 1 | 4 |
| Fatigue | D005221 | HP_0012378 | R53.83 | 1 | — | — | — | 3 | 4 |
| Non-hodgkin lymphoma | D008228 | — | C85.9 | 3 | — | — | — | — | 3 |
| Renal cell carcinoma | D002292 | EFO_0000376 | — | 3 | — | — | — | — | 3 |
| Overactive urinary bladder | D053201 | EFO_1000781 | N32.81 | 3 | — | — | — | — | 3 |
Show 53 more
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Hip osteoarthritis | D015207 | EFO_1000786 | M16 | — | — | — | — | 6 | 6 |
| Arthritis | D001168 | HP_0001369 | M05-M14 | — | — | — | — | 4 | 4 |
| Replacement arthroplasty hip | D019644 | — | — | — | — | — | — | 4 | 4 |
| Musculoskeletal diseases | D009140 | — | — | — | — | — | — | 4 | 4 |
| Avitaminosis | D001361 | EFO_0005878 | E56.9 | — | — | — | — | 3 | 3 |
| Anxiety | D001007 | EFO_0005230 | F41.1 | — | — | — | — | 3 | 3 |
| Irritable bowel syndrome | D043183 | EFO_0000555 | K58 | — | — | — | — | 3 | 3 |
| Heart disease risk factors | D000082742 | — | — | — | — | — | — | 3 | 3 |
| Rheumatic diseases | D012216 | — | M79.0 | — | — | — | — | 3 | 3 |
| Joint diseases | D007592 | HP_0003040 | M12.9 | — | — | — | — | 3 | 3 |
Show 181 more
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Vitamin e |
| INN | phytomenadione |
| Description | (R,R,R)-alpha-tocopherol is an alpha-tocopherol that has R,R,R configuration. The naturally occurring stereoisomer of alpha-tocopherol, it is found particularly in sunflower and olive oils. It has a role as an antioxidant, a nutraceutical, an antiatherogenic agent, an EC 2.7.11.13 (protein kinase C) inhibitor, an anticoagulant, an immunomodulator, an antiviral agent, a micronutrient, an algal metabolite and a plant metabolite. It is an enantiomer of a (S,S,S)-alpha-tocopherol. |
| Classification | Unknown |
| Drug class | — |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | 10191-41-0 |
| RxCUI | — |
| ChEMBL ID | CHEMBL3989727 |
| ChEBI ID | — |
| PubChem CID | 14985 |
| DrugBank | — |
| UNII ID | A034SE7857 (ChemIDplus, GSRS) |
Target
No data
Variants
No data
Financial
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Trends
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Safety
Black-box Warning
Black-box warning for: Citranatal 90 dha, Citranatal assure, Citranatal dha, Citranatal essence, Citranatal harmony, Citranatal harmony 2.1, Citranatal harmony 3.0, Citranatal medley, Citranatal rx, Healthy mamabe well rounded, Marnatal f, Moms choice rx, Natafort, Neonatal complete, Neonatal dha, Nestabs one, O-cal prenatal vitamin, Pnv prenatal plus multivitamin, Pnv prenatal vitamin, Pnv-dha, Pnv-omega, Pnv-select, Pr natal 400, Pr natal 400 ec, Pr natal 430, Pr natal 430 ec, Prenaissance, Prenaissance plus, Prenata, Prenatal plus multivitamin plus dha minicaps, Prenate dha, Prenate elite, Prenate enhance, Prenate essential, Prenate mini, Prenate pixie, Prenate restore, Primacare, Select ob, Select-ob plus dha, Tristart dha, Vitafol, Vitafol fe plus, Vitafol ob, Vitafol-ob plus dha
Adverse Events
Top Adverse Reactions
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1,631 adverse events reported
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